Science Center A243
Personal Office Hours:
M 10:00a-11:30a; T 1:30p-2:30p
- Bachelor of Arts, University of Rochester
- Doctor of Philosophy, University of Washington
- Post-doctoral Fellow, Dartmouth College
- Visiting Assistant Professor, Dartmouth College
NSCI 320: Neuroanatomy
NSCI 324: Neuroanatomy Research Methods
NSCI 201: Introduction to Neuroscience
NSCI 211: Neuroscience Laboratory methods
NSCI 400: The Neurobiology of Addiction
Other teaching interests: Behavioral neuroscience, hormones and behavior, drugs, brain and behavior, learning and memory, research methods
My animal-based research employs both classical and innovative techniques to identify the neurochemistry and the neural circuitry within the brain that underlie associative learning. Current research projects examine how individual cortical regions are involved in different forms of learning (classical conditioning, reward-related learning and stimulus-stimulus learning).
Cortical circuitry, Learning and memory
Robinson S & *Adelman JS (in press) A method for remotely silencing neural activity during discrete phases of learning. The Journal of Visualized Experimentation.
Robinson S, Todd TP, *Pasternak AR, Luikart BW, Skelton PD, Urban DG & Bucci DJ (2014). Chemogenetic silencing of neurons in retrosplenial cortex disrupts sensory preconditioning. The Journal of Neuroscience. 34:10982-10988.
Bucci DJ & Robinson S (2014) Toward a conceptualization of retrohippocampal contributions to learning and memory. Neurobiology of Learning and Memory. 116: 197-207. Cover article
Robinson S, *Poorman CE, *Marder TJ & Bucci DJ (2012). Identification of Functional Circuitry Between Retrosplenial and Postrhinal Cortices During Fear Conditioning. The Journal of Neuroscience. 32:12076-86.
Robinson S & Bucci DJ (2012). Damage to posterior parietal cortex impairs two forms of relational learning. Frontiers in Integrative Neuroscience. doi:10.3389/fnint.2012.00045.
Robinson S & Bucci DJ (2012). Fear conditioning is disrupted by damage to the postsubiculum. Hippocampus. 22:1481-91.
Robinson S, Keene C, *Iaccarino HF, Duane D & Bucci DJ (2011). Involvement of retrosplenial cortex in forming associations between multiple sensory stimuli. Behavioral Neuroscience 125:578-587.
Reward-Related Learning and dopamine signaling
Robinson S, *Rainwater AJ, Hnasko TS & Palmiter RD (2007). Viral restoration of dopamine signaling to the dorsal straitum restores instrumental conditioning to dopamine-deficient mice. Psychopharmacology 191: 567-578.
Robinson S, *Sotak, BS, During M & Palmiter RD (2006). Local production of dopamine in the dorsal striatum restores performance and reversal learning in dopamine deficient mice. Behavioral Neuroscience 120: 196-200.
*Sotak BS, Hnasko TS, Robinson S, Kremer EJ & Palmiter RD (2005). Dysregulation of dopamine signaling in the striatum disrupts feeding. Brain Research 1061:88-96. Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont R, Sotnikova T, Boska P, El-Ghundi M, O’Dowd BF, George SR, Perreault ML, Mannisto PT, Robinson S, Palmiter RD & Tallerico T (2005). Dopamine-mimetic supersensitivity has increased D2HIGH states implying many paths to psychosis. Proceeding of the National Academy of Sciences USA 102:3513-3518.
Robinson S, *Sandstrom SM, Denenberg VH & Palmiter RD (2005). Distinguishing whether dopamine regulates liking, wanting, and/or learning about rewards. Behavioral Neuroscience 119:5-15.
Commentary: Berridge, KC (2005). Espresso reward learning, hold the dopamine. Behavioral Neuroscience 119: 336-341
Commentary: Adelson, R (2005). “Dopamine and desire”. The American Psychological Association, Monitor on Psychology 5: 21-24.
Bamford NS, Robinson S, Palmiter RD, Joyce JA, Moore C & Meshul CK (2004). Dopamine modulates release from corticostriatal terminals. Journal of Neuroscience 24:9541- 9552.
Robinson S, Smith DM, Mizumori SJY & Palmiter RD (2004). Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor agonists and anesthesia. Proceeding of the National Academy of Sciences USA 101: 13329-13334.
Commentary: Surmeier JD (2004). Homeostatic regulation of dopamine neurons without dopamine. Proc. Natl. Acad. Sci 101: 13103-13104.
Commentary: Without dopamine, neurons continue to fire normally. (2005) Research News Howard Hughes Medical Institute, News and Views.
Paladini CA, Robinson S, Morikawa H, Williams JT & Palmiter RD (2003). Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proceeding of the National Academy of Sciences USA 100: 2866-2871.
Robinson S, Freeman P, Moore C, Touchon JC, Krentz L & Meshul CK (2003). Acute and subchronic MPTP administration differentially affects striatal glutamate synaptic function. Experimental Neurology 180: 73-86.
Robinson S, Krentz L, Moore C & Meshul CK (2001). Blockade of NMDA receptors by MK-801 reverses the changes in striatal glutamate immunolabeling in 6-OHDA lesioned rats. Synapse 42: 54-61.
Neuroendocrinology (aggression and reproductive behavior)
Robinson S, Penatti CAA & Clark AS (2011). The role of the androgen receptor in anabolic androgenic steroid-induced aggressive behavior in C57BL/6J and Tfm mice. Hormones & Behavior 61: 67-75
Clark AS, Robinson S, Meerts S, Boisvert E & *Quill K (2011). Determining the contributions of the pelvic and hypogastric nerves to paced mating behavior. Behavioral Neuroscience 125: 668-673.
Clark AS & Robinson S, Boisvert E & *Quill KA (2011). The display of paced mating behavior in a rat model of endometriosis. Physiology & Behavior 104: 722-727.
Wade CB, Robinson S, Shapiro RA & Dorsa DM (2001). Estrogen receptor (ER)a and ERb exhibit unique pharmacological properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology 142: 2336-2342.
Blasberg ME, Robinson S, Henderson LP & Clark AS (1998). Inhibition of estrogen induced sexual receptivity by androgens: role of the androgen receptor. Hormones & Behavior 34: 283-293.
Clark AS, Myers M, Robinson S, Chang P & Henderson LP (1998). Hormone dependent regulation of GABAA receptor g subunit mRNAs in sexually dimorphic regions of the rat brain. Proceeding of the Royal Society of London 265: 1853-1859.
Clark AS, Robinson S & Henderson LP (1997). Dynamics of GABAA receptor binding in the ventromedial hypothalamus during postnatal development in the rat. Developmental Brain Research 103: 195-198.