Science Center A241
- Bachelor of Science, University of British Columbia, Vancouver BC, Canada 1999
- Master of Arts, Queen's University, Kingston ON, Canada 2001
- Doctor of Philosophy, Queen's University, Kingston ON, Canada 2004
Area of Interest:
Neuropharmacology, Behavioral Neuroscience, Attention, Impulse control, Substance Abuse
Tracie Paine is a behavioral neuroscientist whose research uses a combination of behavioral and molecular biological techniques to investigate the neurobiology of cognitive functions such as attention and impulse control. Attention and impulse control are dysregulated in a number of psychiatric conditions including schizophrenia, attention-deficit hyperactivity disorder (ADHD) and substance abuse. Thus, understanding the neurobiology of these cognitive functions will ultimately lead to the development of novel, more effective treatment strategies for these conditions.
Tracie Paine has been awarded National Alliance for Research on Schizophrenia and Depression (NARSAD) Young investigator awards (2006, 2009) in order to pursue research investigating cortical cell signaling pathways and neural circuits regulating attention and impulse control. Her most recent publications appear in the journals Neuropsychopharmacology, Neuropharmacology and Biological Psychiatry.
Paine TA, Neve RL, Carlezon WA Jr. (2009). Attention deficits and hyperactivity following inhibition of cAMP-dependent protein kinase (PKA) within the medial prefrontal cortex of rats. Neuropsychopharmacology, 34, 2143-2155.
Paine TA, Carlezon WA Jr. (2009). Effects of antipsychotic drugs on MK-801-induced attentional deficits in rats. Neuropharmacology, 56, 788-797.
Paine TA, Tomasiewicz HC, Zhang K, Carlezon WA Jr. (2007). Sensitivity of the five-choice serial reaction time task to the effects of various psychotropic drugs in Sprague-Dawley rats. Biological Psychiatry, 62, 687-693.
Paine TA, Olmstead MC (2004). Cocaine disrupts both behavioural inhibition and conditional discrimination in Long-Evans rats. Psychopharmacology, 175, 443-450.
Paine TA, Dringenberg HC, Olmstead MC (2003). Effects of chronic cocaine on cognitive and motor impulsivity: Relation to cortical serotonin mechanisms. Behavioural Brain Research, 147, 135- 147.